Fish Blood Smear Under the Microscope

Fish Blood Smear, Cyprinus carpio

Fish Blood Smear, prepared microscope slide

This is a smear of fish blood stained with Giemsa. Like bird and frog blood, fish red blood cells are oval and keep their nucleus, which makes this slide useful for comparing vertebrate blood.

This is a smear of fish blood from a carp (Cyprinus carpio), stained with Giemsa. Most of the cells are red blood cells, which are oval and have a dark nucleus in the center. That is a key difference from human red blood cells, which are round and have no nucleus. A few darker, smaller cells scattered between them are white blood cells and other blood cells. Students can compare this slide with a human blood smear to see how red blood cells differ between groups of animals.

What to look for

Questions and answers

Do fish red blood cells have a nucleus?

Yes. Fish red blood cells are oval and have a nucleus, like those of birds, reptiles, and amphibians. Mammals are the main group whose mature red blood cells lose their nucleus.

How is fish blood different from human blood under a microscope?

Fish red blood cells are oval with a dark nucleus in the center. Human red blood cells are round, smaller, and have no nucleus, so they have a pale center instead.

Compare it

Category
Vertebrates
Scan magnification
20x
Stain
Giemsa

Viewing this slide in class

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